Anxiety and panic symptoms7 include nausea, chest pain, trembling, tingling, choking, lightheadedness, CBD hemp oil for sale and loss of control. However, in anxiety disorders, a neurotransmitter imbalance6 causes disruption in modulation and regulation, resulting in low serotonin and GABA, excessive norepinephrine and CRH, and high glutamate levels. When we experience anxiety, the amygdala is triggered4by a stimulus or stressor.
Too little norepinephrine can cause depression18 which typically accompanies anxiety disorders. During a panic attack, heart and respiratory rate increase causing palpitations and shortness of breath because the brain needs more oxygen to prepare for the flight and fight response.
The amygdala is the part of the brain where anxiety symptoms originate. Although it doesn’t trigger feelings or thoughts, it dictates how the body reacts. Its primary function is managing fear and our response to situations that we view as potentially dangerous. Anxiety is a normal human reaction when one is faced with trials or difficulties.
But once the problem is resolved, the anxiousness should disappear. For people suffering from an anxiety disorder, the feelings of fear, anxiety, and worry do not go away and typically worsen over time, affecting daily activities and interfering with their quality of life.
CBD activates adenosine receptors, which have an important role in regulating blood flow and heart rate27, and suppressing the release of excitatory neurotransmitters28 like dopamine. Activating these receptors with CBD decreases anxiety symptoms by inhibiting the release of dopamine, slowing down the heart rate, and normalizing blood pressure. GABA24, an inhibitory neurotransmitter, decreases neuron excitability, creating a calming effect and relaxing muscle tone. By blocking the reabsorption of GABA, CBD helps control excitatory neurotransmitters. Tricyclic Antidepressants17 inhibit reabsorption of serotonin and norepinephrine.